San Antonio Missions Roster & Staff
SD Transactions
| Date | Transaction |
| 04/21/23 | RHP Nick Duron assigned to ACL Padres. |
| 04/21/23 | Fort Wayne TinCaps transferred RHP Keegan Collett to the Development List. |
| 04/21/23 | San Antonio Missions activated SS Ripken Reyes. |
| 04/20/23 | RHP Alexander Agramonte assigned to DSL Padres. |
| 04/20/23 | RHP Bernard Jose assigned to DSL Padres. |
| 04/20/23 | RHP Jimmy Reyes assigned to DSL Padres. |
| 04/20/23 | RHP Dariel Polanco assigned to DSL Padres. |
| 04/20/23 | RHP Anthony Ortiz assigned to DSL Padres. |
| 04/20/23 | San Diego Padres optioned 3B Brandon Dixon to El Paso Chihuahuas. |
| 04/20/23 | San Diego Padres signed free agent RHP Alexander Agramonte to a minor league contract. |
| 04/20/23 | San Diego Padres signed free agent RHP Anthony Ortiz to a minor league contract. |
| 04/20/23 | San Diego Padres signed free agent RHP Jimmy Reyes to a minor league contract. |
| 04/20/23 | San Diego Padres signed free agent RHP Dariel Polanco to a minor league contract. |
| 04/20/23 | San Diego Padres signed free agent RHP Bernard Jose to a minor league contract. |
| 04/19/23 | RHP Darlin Mendez assigned to DSL Padres. |
| 04/19/23 | SS Eric Valdez assigned to DSL Padres. |
| 04/19/23 | LHP Yovannki Pascual assigned to DSL Padres. |
| 04/19/23 | 2B Eduarlin Tejeda assigned to DSL Padres. |
| 04/19/23 | RHP Johan Minaya assigned to DSL Padres. |
| 04/19/23 | San Diego Padres recalled LHP Ray Kerr from El Paso Chihuahuas. |
| 04/19/23 | San Antonio Missions transferred RHP Henry Henry to the Development List. |
| 04/19/23 | RHP Alek Jacob assigned to San Antonio Missions. |
| 04/19/23 | San Diego Padres signed free agent RHP Darlin Mendez to a minor league contract. |
| 04/19/23 | San Diego Padres signed free agent RHP Johan Minaya to a minor league contract. |
| 04/19/23 | San Diego Padres signed free agent SS Eric Valdez to a minor league contract. |
| 04/18/23 | RHP Matt Boswell retired. |
| 04/18/23 | RHP Anderson Espinoza roster status changed by El Paso Chihuahuas. |
| 04/18/23 | San Diego Padres sent LHP Drew Pomeranz on a rehab assignment to Lake Elsinore Storm. |
| 04/18/23 | San Diego Padres sent LHP Drew Pomeranz on a rehab assignment to Lake Elsinore Storm. |
| 04/17/23 | San Diego Padres recalled 3B Brandon Dixon and from El Paso Chihuahuas. |
| 04/16/23 | El Paso Chihuahuas activated RHP Domingo Tapia. |
| 04/16/23 | San Diego Padres optioned 3B Brandon Dixon to El Paso Chihuahuas. |
| 04/16/23 | San Diego Padres optioned RHP Domingo Tapia to El Paso Chihuahuas. |
| 04/16/23 | San Diego Padres recalled RHP Reiss Knehr from El Paso Chihuahuas. |
| 04/16/23 | San Diego Padres recalled C Brett Sullivan from El Paso Chihuahuas. |
| 04/16/23 | San Diego Padres sent RHP Joe Musgrove on a rehab assignment to Lake Elsinore Storm. |
| 04/15/23 | SS Kervin Pichardo assigned to Fort Wayne TinCaps from ACL Padres. |
| 04/15/23 | San Diego Padres sent CF Adam Engel on a rehab assignment to El Paso Chihuahuas. |
| 04/15/23 | Fort Wayne TinCaps placed 3B Nerwilian Cedeño on the 7-day injured list. |
| 04/15/23 | SS Kervin Pichardo assigned to Fort Wayne TinCaps from ACL Padres. |
| 04/11/23 | RHP Carter Loewen assigned to ACL Padres from Lake Elsinore Storm. |
| 04/11/23 | San Diego Padres sent LHP Drew Pomeranz on a rehab assignment to El Paso Chihuahuas. |
| 04/11/23 | RHP Dwayne Matos assigned to Lake Elsinore Storm. |
| 04/11/23 | Lake Elsinore Storm activated RHP Dwayne Matos. |
| 04/11/23 | RHP Carter Loewen assigned to ACL Padres from Lake Elsinore Storm. |
| 04/09/23 | CF Ray-Patrick Didder assigned to ACL Padres. |
| 04/09/23 | El Paso Chihuahuas activated C Michael Cantu. |
| 04/09/23 | San Diego Padres recalled 3B Brandon Dixon, and from El Paso Chihuahuas. |
| 04/07/23 | RHP Erick Batista assigned to DSL Padres. |
| 04/07/23 | San Diego Padres signed free agent CF Ray-Patrick Didder to a minor league contract. |