San Antonio Missions Roster & Staff
SD Transactions
| Date | Transaction |
| 06/15/22 | San Antonio Missions released SS Ike Freeman. |
| 06/15/22 | San Antonio Missions activated LHP Osvaldo Hernandez from the 7-day injured list. |
| 06/15/22 | San Antonio Missions activated SS Korry Howell from the 7-day injured list. |
| 06/15/22 | San Antonio Missions activated 1B Yorman Rodriguez from the 7-day injured list. |
| 06/15/22 | C Juan Zabala assigned to Lake Elsinore Storm from San Antonio Missions. |
| 06/15/22 | 3B Kelvin Alarcon assigned to ACL Padres from San Antonio Missions. |
| 06/15/22 | 2B Willmert Paula assigned to ACL Padres from San Antonio Missions. |
| 06/15/22 | 2B Reinaldo Ilarraza assigned to ACL Padres from San Antonio Missions. |
| 06/14/22 | El Paso Chihuahuas activated OF Shogo Akiyama from the 7-day injured list. |
| 06/14/22 | San Antonio Missions sent RHP Ethan Routzahn on a rehab assignment to Fort Wayne TinCaps. |
| 06/14/22 | San Antonio Missions sent RHP Ethan Routzahn on a rehab assignment to Fort Wayne TinCaps. |
| 06/14/22 | RHP Ethan Routzahn assigned to Fort Wayne TinCaps from San Antonio Missions. |
| 06/14/22 | LHP Fred Schlichtholz assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 06/14/22 | RHP Luis Madrazo assigned to Fort Wayne TinCaps from San Antonio Missions. |
| 06/14/22 | RHP Brandon Komar assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 06/14/22 | San Antonio Missions activated LHP Fred Schlichtholz. |
| 06/14/22 | San Antonio Missions activated LHP Fred Schlichtholz. |
| 06/14/22 | San Antonio Missions placed SS Korry Howell on the 7-day injured list. |
| 06/14/22 | San Antonio Missions sent RHP Ethan Routzahn on a rehab assignment to Fort Wayne TinCaps. |
| 06/14/22 | San Antonio Missions sent RHP Ethan Routzahn on a rehab assignment to Fort Wayne TinCaps. |
| 06/14/22 | RHP Brandon Komar assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 06/14/22 | LHP Fred Schlichtholz assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 06/14/22 | RHP Ethan Routzahn assigned to Fort Wayne TinCaps from San Antonio Missions. |
| 06/14/22 | RHP Luis Madrazo assigned to Fort Wayne TinCaps from San Antonio Missions. |
| 06/13/22 | LHP Danny Denz assigned to ACL Padres from Fort Wayne TinCaps. |
| 06/13/22 | RHP Wen-Hua Sung assigned to ACL Padres from Fort Wayne TinCaps. |
| 06/13/22 | RHP Wen-Hua Sung assigned to ACL Padres from Fort Wayne TinCaps. |
| 06/13/22 | LHP Danny Denz assigned to ACL Padres from Fort Wayne TinCaps. |
| 06/12/22 | El Paso Chihuahuas activated OF Brent Rooker. |
| 06/12/22 | El Paso Chihuahuas activated RHP Dinelson Lamet. |
| 06/12/22 | El Paso Chihuahuas activated RHP Reiss Knehr. |
| 06/12/22 | El Paso Chihuahuas activated RHP Jose Quezada. |
| 06/12/22 | San Diego Padres optioned OF Brent Rooker to El Paso Chihuahuas. |
| 06/12/22 | San Diego Padres optioned RHP Reiss Knehr to El Paso Chihuahuas. |
| 06/12/22 | San Diego Padres selected the contract of RHP Kyle Tyler from El Paso Chihuahuas. |
| 06/12/22 | RHP Dinelson Lamet assigned to El Paso Chihuahuas from San Antonio Missions. |
| 06/12/22 | RHP Dinelson Lamet assigned to El Paso Chihuahuas from San Antonio Missions. |
| 06/11/22 | Lake Elsinore Storm sent OF Michael Green on a rehab assignment to ACL Padres. |
| 06/11/22 | Lake Elsinore Storm sent IF Bryan Torres on a rehab assignment to ACL Padres. |
| 06/11/22 | Lake Elsinore Storm sent OF Michael Green on a rehab assignment to ACL Padres. |
| 06/11/22 | ACL Padres released RHP Adrian De Los Santos. |
| 06/11/22 | San Antonio Missions sent RHP Ethan Routzahn on a rehab assignment to ACL Padres. |
| 06/11/22 | San Diego Padres recalled LHP Ray Kerr from El Paso Chihuahuas. |
| 06/11/22 | San Diego Padres recalled OF Brent Rooker from El Paso Chihuahuas. |
| 06/11/22 | San Diego Padres recalled RHP Reiss Knehr from El Paso Chihuahuas. |
| 06/11/22 | Fort Wayne TinCaps activated OF Robert Hassell III from the 7-day injured list. |
| 06/11/22 | Lake Elsinore Storm sent OF Michael Green on a rehab assignment to ACL Padres. |
| 06/11/22 | Lake Elsinore Storm sent IF Bryan Torres on a rehab assignment to ACL Padres. |
| 06/11/22 | Lake Elsinore Storm sent OF Michael Green on a rehab assignment to ACL Padres. |
| 06/11/22 | San Antonio Missions sent RHP Ethan Routzahn on a rehab assignment to ACL Padres. |