San Antonio Missions Roster & Staff
SD Transactions
| Date | Transaction |
| 06/10/22 | Lake Elsinore Storm sent C Gilberto Vizcarra on a rehab assignment to ACL Padres. |
| 06/10/22 | C Alejandro Hernandez assigned to ACL Padres from Lake Elsinore Storm. |
| 06/10/22 | 2B Robinson Cano assigned to El Paso Chihuahuas. |
| 06/10/22 | El Paso Chihuahuas activated 2B Robinson Cano. |
| 06/10/22 | Fort Wayne TinCaps activated OF Corey Rosier from the 7-day injured list. |
| 06/10/22 | Fort Wayne TinCaps activated OF Corey Rosier from the 7-day injured list. |
| 06/10/22 | Lake Elsinore Storm sent C Gilberto Vizcarra on a rehab assignment to ACL Padres. |
| 06/10/22 | C Alejandro Hernandez assigned to ACL Padres from Lake Elsinore Storm. |
| 06/10/22 | San Antonio Missions placed 3B Rafael Fermin on the 60-day injured list. |
| 06/10/22 | San Antonio Missions activated OF Tirso Ornelas from the 7-day injured list. |
| 06/09/22 | El Paso Chihuahuas sent RHP Jose Quezada on a rehab assignment to ACL Padres. |
| 06/09/22 | El Paso Chihuahuas sent RHP Jose Quezada on a rehab assignment to ACL Padres. |
| 06/09/22 | El Paso Chihuahuas released RHP Yusmeiro Petit. |
| 06/09/22 | El Paso Chihuahuas released 3B Aderlin Rodriguez. |
| 06/09/22 | El Paso Chihuahuas activated RHP Jesse Scholtens from the 7-day injured list. |
| 06/09/22 | 2B Reinaldo Ilarraza assigned to San Antonio Missions from El Paso Chihuahuas. |
| 06/09/22 | San Diego Padres sent RHP Kyle Tyler outright to El Paso Chihuahuas. |
| 06/09/22 | 3B Kelvin Alarcon assigned to San Antonio Missions from El Paso Chihuahuas. |
| 06/09/22 | Fort Wayne TinCaps placed LHP Danny Denz on the 7-day injured list. |
| 06/09/22 | 2B Reinaldo Ilarraza assigned to San Antonio Missions from El Paso Chihuahuas. |
| 06/09/22 | 3B Kelvin Alarcon assigned to San Antonio Missions from El Paso Chihuahuas. |
| 06/08/22 | 1B Kyle Martin assigned to El Paso Chihuahuas. |
| 06/08/22 | Fort Wayne TinCaps activated LHP Fred Schlichtholz from the 7-day injured list. |
| 06/08/22 | Fort Wayne TinCaps activated RHP Felix Minjarez. |
| 06/08/22 | San Diego Padres signed free agent 1B Kyle Martin to a minor league contract. |
| 06/07/22 | Lake Elsinore Storm sent OF James Wood on a rehab assignment to ACL Padres. |
| 06/07/22 | 2B Willmert Paula assigned to San Antonio Missions from ACL Padres. |
| 06/07/22 | El Paso Chihuahuas activated 2B Esteury Ruiz. |
| 06/07/22 | El Paso Chihuahuas placed RHP Jordan Brink on the 7-day injured list. |
| 06/07/22 | El Paso Chihuahuas activated LF Taylor Kohlwey from the 7-day injured list. |
| 06/07/22 | El Paso Chihuahuas placed OF Shogo Akiyama on the 7-day injured list. |
| 06/07/22 | San Diego Padres recalled LHP Adrian Morejon from El Paso Chihuahuas. |
| 06/07/22 | 2B Esteury Ruiz assigned to El Paso Chihuahuas from San Antonio Missions. |
| 06/07/22 | SS Ripken Reyes assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 06/07/22 | Lake Elsinore Storm sent OF James Wood on a rehab assignment to ACL Padres. |
| 06/07/22 | LHP Matt Lachappa roster status changed by Lake Elsinore Storm. |
| 06/07/22 | C Juan Zabala assigned to San Antonio Missions. |
| 06/07/22 | San Antonio Missions activated SS Ripken Reyes. |
| 06/07/22 | 2B Willmert Paula assigned to San Antonio Missions from ACL Padres. |
| 06/07/22 | 2B Esteury Ruiz assigned to El Paso Chihuahuas from San Antonio Missions. |
| 06/07/22 | SS Ripken Reyes assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 06/06/22 | SS Victor Acosta assigned to ACL Padres. |
| 06/06/22 | RHP Luis Madrazo assigned to ACL Padres. |
| 06/06/22 | 2B Jake Perez assigned to ACL Padres. |
| 06/06/22 | C Colton Bender assigned to ACL Padres. |
| 06/06/22 | C Carlos Rodriguez assigned to ACL Padres. |
| 06/06/22 | RHP Adrian De Los Santos assigned to ACL Padres. |
| 06/06/22 | RHP Adrian Luna assigned to ACL Padres. |
| 06/06/22 | ACL Padres activated 3B Juan Murillo. |
| 06/06/22 | ACL Padres activated RHP Jarlin Susana. |