San Antonio Missions Roster & Staff
SD Transactions
| Date | Transaction |
| 06/06/22 | RHP Walki Lezan assigned to ACL Padres. |
| 06/06/22 | OF Eddy Beltre assigned to ACL Padres. |
| 06/06/22 | RHP Manuel Castro assigned to ACL Padres. |
| 06/06/22 | 3B Juan Murillo assigned to ACL Padres. |
| 06/06/22 | SS Rosman Verdugo assigned to ACL Padres. |
| 06/06/22 | OF Samuel Zavala assigned to ACL Padres. |
| 06/06/22 | RHP Miguel Mendez assigned to ACL Padres. |
| 06/06/22 | RHP Miguel Rondon assigned to ACL Padres. |
| 06/06/22 | RHP Jarlin Susana assigned to ACL Padres. |
| 06/06/22 | OF Daniel Montesino assigned to ACL Padres. |
| 06/06/22 | RHP Henry Baez assigned to ACL Padres. |
| 06/06/22 | ACL Padres placed OF Daniel Montesino on the 60-day injured list. |
| 06/06/22 | RF Joshua Mears assigned to ACL Padres from Fort Wayne TinCaps. |
| 06/06/22 | RHP Luis Madrazo assigned to San Antonio Missions from ACL Padres. |
| 06/06/22 | 3B Rafael Fermin assigned to San Antonio Missions from ACL Padres. |
| 06/06/22 | DSL Padres placed RHP Alejandro Lugo on the restricted list. |
| 06/06/22 | DSL Padres released LF Axcel Peralta. |
| 06/06/22 | DSL Padres released OF Samuel Vallejo. |
| 06/06/22 | DSL Padres released OF Carlos Vergara. |
| 06/06/22 | DSL Padres released SS Ignacio Ramos. |
| 06/06/22 | El Paso Chihuahuas activated RHP Pedro Avila. |
| 06/06/22 | LHP Daniel Camarena roster status changed by El Paso Chihuahuas. |
| 06/06/22 | San Diego Padres sent RHP Pedro Avila outright to El Paso Chihuahuas. |
| 06/06/22 | San Diego Padres optioned LHP Adrian Morejon to El Paso Chihuahuas. |
| 06/06/22 | RF Joshua Mears assigned to ACL Padres from Fort Wayne TinCaps. |
| 06/06/22 | SS Ike Freeman assigned to San Antonio Missions. |
| 06/06/22 | San Antonio Missions transferred 3B Brandon Dixon from the 7-day injured list to the 60-day injured list. |
| 06/06/22 | RHP Gabe Mosser roster status changed by San Antonio Missions. |
| 06/06/22 | CF Robbie Podorsky roster status changed by San Antonio Missions. |
| 06/06/22 | San Antonio Missions transferred 3B Brandon Dixon from the 7-day injured list to the 60-day injured list. |
| 06/06/22 | San Antonio Missions placed LHP Osvaldo Hernandez on the 7-day injured list. |
| 06/06/22 | San Antonio Missions placed 1B Yorman Rodriguez on the 7-day injured list. |
| 06/06/22 | CF Robbie Podorsky roster status changed by San Antonio Missions. |
| 06/06/22 | San Antonio Missions placed 3B Rafael Fermin on the 60-day injured list. |
| 06/06/22 | San Antonio Missions placed OF Jorge Ona on the 7-day injured list. |
| 06/06/22 | RHP Gabe Mosser roster status changed by San Antonio Missions. |
| 06/06/22 | 3B Rafael Fermin assigned to San Antonio Missions from ACL Padres. |
| 06/06/22 | San Diego Padres optioned RHP Michel Baez to San Antonio Missions. |
| 06/06/22 | RHP Luis Madrazo assigned to San Antonio Missions from ACL Padres. |
| 06/05/22 | ACL Padres placed LHP Jagger Haynes on the 60-day injured list. |
| 06/05/22 | RHP Bradgley Rodriguez assigned to ACL Padres. |
| 06/05/22 | ACL Padres placed RHP Jose Luis Reyes on the 60-day injured list. |
| 06/05/22 | ACL Padres placed LHP Jagger Haynes on the 60-day injured list. |
| 06/05/22 | 2B Oliver Cedeno assigned to DSL Padres. |
| 06/05/22 | OF Eizon Delgado assigned to DSL Padres. |
| 06/05/22 | El Paso Chihuahuas activated OF Brent Rooker. |
| 06/05/22 | San Diego Padres optioned OF Brent Rooker to El Paso Chihuahuas. |
| 06/04/22 | C Alejandro Hernandez assigned to Lake Elsinore Storm from ACL Padres. |
| 06/04/22 | C Alejandro Hernandez assigned to Lake Elsinore Storm from ACL Padres. |
| 06/04/22 | San Antonio Missions placed RHP Matt Waldron on the 7-day injured list. |